Caucasian people as carries of one of the defective cystic fibrosis causing genes

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Caucasian people as carries of one of the defective cystic fibrosis causing genes

Email An year-old California boy has reportedly been asked to leave school because he carries a cystic fibrosis gene and may pose a health risk to other students at the school with the disease. CBS San Francisco reports however that the boy, Colman Chadam, does not have the incurable respiratory disease that is not contagious, but is only a carrier of genetic mutations.

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The district wants Colman to transfer to a nearby school district. People with cystic fibrosis can carry bacteria that are potentially dangerous to others with the condition.

Colman's parents noted on a form the boy had the gene, then nearly two months into the school year, officials at Jordan Middle School in Palo Alto, Calif.

It is caused by a defective gene and its resulting proteins producing unusually thick mucus that may clog the lungs leading to dangerous infections or obstruct the pancreas, preventing the body from breaking down and absorbing nutrients. Fear of spreading those infections to other students with the disease was what prompted the school board's actions.

The Chronicle notes non-siblings with the disease are advised to stay at least three to six feet away from each other.

Cystic Fibrosis Among White Americans | Anthropology

But Colman's parents argue their child has been cleared by doctors as not having the disease and thus not posing a risk to others. Millions of Americans carry a defective cystic fibrosis gene, according to the National Institutes of Healthbut don't show any symptoms because a person must inherit a defective gene from each parent to develop the disease.

Caucasian people as carries of one of the defective cystic fibrosis causing genes

Laurie Fink, a spokeswoman for the Cystic Fibrosis Foundation told Life's Little Mysteries that is it is possible for someone to carry two defective genes without showing signs of the condition.

The Chadams have taken the case to court and a judge will hold a hearing on his possible return to Jordan, according to CBS San Francisco.People with CF have inherited two copies of the defective CF gene -- one copy from each parent.

Both parents must have at least one copy of the defective gene. People with only one copy of the defective CF gene are called carriers, but they do not have the disease (approximately 1 in 23 of the general population that is 12 million people!).

Topic Overview

Cystic fibrosis (CF) is one of the most common life threatening genetic diseases, affecting approximately 1 out of 3, people. The severity of CF varies, with some children showing symptoms at birth, and others not . Parents carrying one good copy of the CF gene (R) and one bad copy of the mutated CF gene (r) are called carriers.

When both parents transmit a bad copy of the CF gene to their offspring, the child will suffer from cystic fibrosis.

Children who inherit just one bad copy will be carriers like their parents and can transmit the gene to their children. Heterozygous carriers of autosomal recessive genes are more common than the affected homozygous individuals Mutant alleles may remain in a __________state without phenotypic expression in a family for numerous generations.

One person in every 29 people who are Caucasian are carriers of an altered CF gene.

FAQ: Carrier Testing for Cystic Fibrosis | Patient Education | UCSF Medical Center

In other race or ethnic groups, one in 46 Hispanic Americans, one in 65 African Americans and one in 90 Asian Americans carry an altered CF gene. If both parents carry a defective cystic fibrosis gene, each pregnancy has a 25 percent chance of producing a child with cystic fibrosis.

During pregnancy, an accurate diagnosis of cystic fibrosis in the fetus is usually possible.

Caucasian people as carries of one of the defective cystic fibrosis causing genes
FAQ: Carrier Testing for Cystic Fibrosis | Patient Education | UCSF Medical Center